What is PDRN / Salmon DNA therapy?+
PDRN (Polydeoxyribonucleotide) is a purified extract of DNA fragments derived from salmon sperm — which has a nucleotide composition highly compatible with human DNA. When injected into the skin, these polynucleotide chains activate cell surface receptors (primarily A2A adenosine receptors) that trigger anti-inflammatory signaling, growth factor release, and accelerated tissue repair. BHRC West Hollywood uses pharmaceutical-grade PDRN products with clinical research supporting their efficacy.
Is PDRN the same as Rejuran?+
Rejuran is the brand name of the most well-known PDRN injectable from South Korea. BHRC West Hollywood may use Rejuran or comparable high-quality pharmaceutical PDRN products. The active ingredient in all PDRN products is the same polynucleotide complex — brand differences relate to concentration, formulation, and delivery mechanism. Your BHRC provider will discuss the specific product used at your consultation.
How is PDRN different from PRP at BHRC West Hollywood?+
PRP uses concentrated growth factors from your own blood. PDRN provides nucleotide building blocks that activate cellular repair receptors through a different mechanism. PRP delivers immediate growth factor signaling; PDRN works more gradually through receptor activation and DNA repair pathways. They are complementary — many BHRC West Hollywood patients combine both for a comprehensive regenerative approach.
Is PDRN / Salmon DNA safe for all skin types?+
Yes. PDRN has excellent biocompatibility and is generally well-tolerated by all skin types and Fitzpatrick classifications. Because it is derived from purified salmon sperm DNA and not a living organism, the allergy risk is very low. Patients with fish allergies should disclose this before treatment. BHRC West Hollywood performs a brief health screening before any injectable treatment.
What does PDRN treat at BHRC West Hollywood?+
PDRN at BHRC West Hollywood is used for facial skin rejuvenation and anti-aging, under-eye dark circles and hollows (tear trough), acne scar improvement, skin hydration and plumping, scalp health and hair follicle support, and as a healing accelerant after ablative procedures like CO2 laser or Morpheus8.
How many PDRN sessions do I need?+
BHRC West Hollywood recommends an initial series of 3–6 sessions spaced 2–3 weeks apart. Many patients notice progressive improvement in skin hydration and texture from the first session. Full results from the initial series are apparent at 2–3 months. Maintenance sessions every 3–6 months help sustain and build on the results.
What is the PDRN treatment experience like at BHRC?+
PDRN is injected using very fine needles or a specialized injector device into the intradermal layer. BHRC West Hollywood applies topical numbing cream before treatment. The injections are performed quickly across the treatment area using a micro-papule or linear threading technique. Mild redness and swelling typically resolve within 24 hours. There is no significant downtime.
Can I combine PDRN with other treatments at BHRC?+
Yes. PDRN is one of the most versatile regenerative add-ons. It pairs well with PRP (complementary mechanisms), microneedling (same-session topical application), Morpheus8 (post-treatment to accelerate healing), and HydraFacial (applied during the infusion step). BHRC West Hollywood providers design combined regenerative protocols based on your specific skin goals.
