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Mitochondria-Targeted Peptide

SS-31 10mg

Protects against oxidative stress

SS-31 (Elamipretide) is a highly specialized mitochondria-targeting peptide that selectively concentrates within mitochondrial membranes to protect against oxidative damage and restore cellular energy production. By stabilizing cardiolipin—a critical phospholipid essential for optimal mitochondrial function—SS-31 enhances cellular resilience, improves energy metabolism, and supports comprehensive mitochondrial health for enhanced vitality, cardiovascular protection, neuroprotection, and healthy aging at the cellular level.

10mg

Therapeutic Dose

SC

Subcutaneous

Daily

Administration

4-12

Week Protocols

SS-31 Formulation

Pharmaceutical-grade mitochondria-targeting peptide designed to protect against oxidative stress, restore cellular energy production, and support comprehensive mitochondrial health through selective cardiolipin stabilization.

What is SS-31?

SS-31 (Elamipretide) is a novel mitochondria-targeting peptide specifically engineered to selectively accumulate within the inner mitochondrial membrane, where it binds to and stabilizes cardiolipin—a unique phospholipid essential for optimal mitochondrial structure and function. This targeted mechanism distinguishes SS-31 from other therapies, as it directly addresses mitochondrial dysfunction at its source rather than providing generalized antioxidant effects. Mitochondria serve as the powerhouses of our cells, generating the energy (ATP) required for all biological processes, and their proper function is critical for cellular health, longevity, and disease prevention.

Cardiolipin plays a fundamental role in maintaining the structural integrity of mitochondrial membranes and optimizing the function of the electron transport chain responsible for energy production. However, cardiolipin is highly susceptible to oxidative damage from reactive oxygen species (ROS), leading to mitochondrial dysfunction, reduced energy output, increased cellular damage, and accelerated aging. SS-31’s unique mechanism involves selectively protecting cardiolipin from oxidative stress, stabilizing mitochondrial membrane architecture, reducing ROS production, and restoring efficient energy metabolism within damaged or aging mitochondria.

By targeting the root cause of mitochondrial dysfunction, SS-31 therapy offers comprehensive benefits for cellular health, cardiovascular function, neurological protection, metabolic efficiency, and healthy aging. Research demonstrates SS-31’s potential for improving energy production in tissues with high metabolic demands (heart, brain, muscles), protecting against ischemic injury, reducing inflammation, enhancing exercise capacity, supporting cognitive function, and promoting cellular resilience against age-related decline. This makes SS-31 particularly valuable for individuals seeking to optimize mitochondrial health, enhance physical and mental performance, protect against cardiovascular and neurodegenerative conditions, support recovery from cellular stress or injury, and promote comprehensive longevity and vitality at the cellular level.

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Mitochondrial Protection Mechanism

SS-31 enhances cellular health through selective mitochondrial membrane targeting, cardiolipin stabilization, and oxidative stress reduction for comprehensive mitochondrial function restoration and cellular energy optimization.

Cardiolipin Stabilization

Selectively binds to cardiolipin in the inner mitochondrial membrane, protecting this critical phospholipid from oxidative damage and preserving optimal mitochondrial structure and electron transport chain function.

ROS Reduction

Dramatically reduces reactive oxygen species (ROS) production within mitochondria by optimizing electron transport efficiency, protecting cells from oxidative stress and preventing damage to proteins, lipids, and DNA.

Energy Production Enhancement

Restores efficient ATP synthesis in damaged or aging mitochondria by stabilizing membrane architecture and improving electron transport chain function, dramatically increasing cellular energy availability and metabolic capacity.

Why Consider SS-31?

Cardiovascular Protection

Enhances cardiac mitochondrial function, protects heart tissue from ischemic injury, improves exercise tolerance, and supports overall cardiovascular health through enhanced myocardial energy metabolism and oxidative stress reduction.

Neuroprotection & Cognitive Support

Protects neuronal mitochondria from oxidative damage, supports brain energy metabolism, enhances cognitive function and mental clarity, and provides defense against neurodegenerative processes and age-related cognitive decline.

Enhanced Cellular Energy

Dramatically increases ATP production in damaged or aging mitochondria, reducing fatigue and enhancing overall energy levels, physical stamina, and metabolic capacity for improved daily performance and vitality.

Anti-Aging & Longevity

Reverses age-related mitochondrial decline by restoring youthful mitochondrial function, reducing cellular senescence, protecting against oxidative damage, and supporting comprehensive healthspan extension at the cellular level.

Oxidative Stress Protection

Provides comprehensive cellular defense against reactive oxygen species (ROS) and oxidative damage to proteins, lipids, and DNA, preserving cellular integrity and reducing inflammation throughout the body.

Exercise Performance & Recovery

Improves skeletal muscle mitochondrial function, enhances exercise capacity and endurance, accelerates post-exercise recovery, and supports optimal metabolic adaptation to physical training for superior athletic performance.

How It Works at BHRC

Our medical team guides you through every step—from initial consultation to ongoing optimization.

Comprehensive Evaluation

Detailed health assessment including cardiovascular function, energy levels, cognitive performance, and mitochondrial health indicators to determine SS-31 therapy candidacy.

Baseline Testing

Complete laboratory panel measuring metabolic markers, oxidative stress indicators, cardiac function, and baseline biomarkers to track SS-31 therapy effectiveness.

Personalized Protocol

Customized SS-31 dosing schedule and administration plan tailored to your specific health goals, cardiovascular status, and therapeutic objectives for optimal mitochondrial restoration.

Ongoing Monitoring

Regular progress tracking, biomarker reassessment, protocol adjustments, and medical guidance to maximize mitochondrial benefits and ensure safe, effective SS-31 therapy.

Is SS-31 Right for You?

SS-31 is a highly specific mitochondria-targeting peptide with demonstrated safety in extensive clinical research. Our medical team performs thorough cardiovascular and metabolic assessments to ensure appropriate candidacy and optimal dosing for your individual health profile and therapeutic objectives.

  • Mitochondria-Selective — SS-31 specifically targets mitochondrial membranes without affecting other cellular structures, ensuring precise therapeutic action with minimal off-target effects.
  • Clinically Validated — Extensive research and clinical trials demonstrate SS-31’s safety profile and therapeutic efficacy for cardiovascular protection, neuroprotection, and mitochondrial health support.
  • Cardioprotective Mechanism — SS-31’s unique cardiolipin-stabilizing action provides comprehensive cardiovascular benefits without disrupting normal cardiac function or hormonal balance.
  • Physician-Directed Therapy — All SS-31 treatment is medically supervised with comprehensive health screening, cardiovascular assessment, monitoring, and personalized protocol management for safety and optimal results.
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1000x

Greater mitochondrial concentration compared to other cellular compartments due to selective targeting

40%

Average reduction in mitochondrial ROS production with SS-31 treatment in clinical studies

Frequently Asked

SS-31 (Elamipretide) is a mitochondria-targeting peptide that selectively accumulates within the inner mitochondrial membrane where it binds to and stabilizes cardiolipin—a unique phospholipid essential for optimal mitochondrial structure and function. This targeted mechanism protects cardiolipin from oxidative damage, reduces reactive oxygen species (ROS) production, preserves mitochondrial membrane integrity, and restores efficient energy production in damaged or aging mitochondria. By addressing mitochondrial dysfunction at its source, SS-31 provides comprehensive benefits for cellular energy, cardiovascular health, neuroprotection, and healthy aging.

SS-31 therapy provides comprehensive mitochondrial benefits including enhanced cardiovascular function and exercise tolerance, improved cardiac protection against ischemic injury, significant neuroprotection and cognitive support, dramatically increased cellular energy and reduced fatigue, powerful antioxidant effects and oxidative stress reduction, reversal of age-related mitochondrial decline, improved exercise performance and faster recovery, enhanced metabolic efficiency, reduced inflammation throughout the body, and comprehensive cellular resilience for optimal healthspan. Many patients experience improved energy, mental clarity, physical endurance, and overall vitality.

SS-31 is administered via subcutaneous injection, similar to insulin injections, allowing for convenient self-administration after proper training. The standard therapeutic dose is 10mg administered daily for optimal mitochondrial protection and restoration. Treatment protocols typically run 4-12 weeks depending on individual health goals and therapeutic response, with many individuals benefiting from periodic treatment cycles to maintain optimal mitochondrial function. SS-31 selectively targets mitochondria within hours of administration, with maximal mitochondrial concentration achieved within 24 hours. Your BHRC physician will customize the protocol based on your cardiovascular health, metabolic status, and specific objectives.

Many individuals notice increased energy levels and reduced fatigue within the first 1-2 weeks of SS-31 therapy as mitochondrial function begins to improve. Cardiovascular benefits such as enhanced exercise tolerance and improved endurance typically become apparent within 2-4 weeks of consistent treatment. More significant improvements in cognitive function, metabolic efficiency, recovery capacity, and overall vitality generally develop over 4-8 weeks as cumulative mitochondrial restoration occurs. For comprehensive cardiovascular protection, neuroprotection, and anti-aging benefits, protocols of 8-12 weeks are recommended to allow full mitochondrial regeneration and oxidative stress reduction throughout high-demand tissues.

SS-31 has demonstrated excellent safety in clinical trials with minimal adverse effects due to its highly selective mitochondrial targeting. The most commonly reported side effects are mild and include temporary injection site reactions (redness, mild discomfort) that typically resolve quickly. Rare individuals may experience mild headaches or fatigue during the initial treatment period as cellular metabolism adjusts. SS-31 should be used cautiously in individuals with certain acute cardiac conditions, active malignancies, or specific metabolic disorders. Pregnant or nursing women should avoid SS-31 therapy. Comprehensive cardiovascular evaluation and medical assessment ensure appropriate candidacy and safe protocol implementation.

Yes, SS-31 synergizes exceptionally well with complementary therapies and is frequently incorporated into comprehensive health optimization protocols. SS-31 is often combined with NAD+ therapy for enhanced mitochondrial energy production, peptide therapies targeting muscle growth or recovery (BPC-157, TB-500) for amplified regenerative effects, antioxidant supplementation (glutathione, CoQ10) for comprehensive oxidative stress protection, cardiovascular support therapies, and targeted exercise programs for optimized mitochondrial adaptation. Many patients integrate SS-31 with hormone optimization, metabolic therapies, or longevity interventions for synergistic benefits. Your BHRC physician will design an integrated protocol optimized for your cardiovascular health, performance goals, and therapeutic objectives.

SS-31 therapy is typically not covered by insurance as it’s considered preventive, regenerative, and performance-enhancing medicine focused on mitochondrial optimization and longevity rather than treatment for acute disease. BHRC offers transparent pricing and flexible payment options to make this advanced mitochondrial therapy accessible. Many patients find the investment highly worthwhile given the comprehensive benefits for cardiovascular health, energy, cognitive function, exercise performance, and healthy aging. Some health savings accounts (HSA) or flexible spending accounts (FSA) may cover SS-31 therapy—consult your provider. Our team can provide detailed cost information and discuss payment plans during your consultation.

Begin Your Transformation

Schedule a consultation with our medical team to learn if SS-31 peptide therapy is right for your wellness journey.

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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. SS-31 is provided for mitochondrial health optimization, cardiovascular support, and cellular energy enhancement under physician supervision. Individual results may vary. A consultation with our medical team and baseline cardiovascular and metabolic testing are required to determine if this therapy is appropriate for you.

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