Mitochondrial Peptide
Advanced cellular energy and metabolic optimization
MOTS-c is a mitochondrial-derived peptide that enhances cellular energy production, improves metabolic function, and supports healthy aging by optimizing mitochondrial efficiency. This naturally occurring peptide regulates glucose metabolism, promotes fat oxidation, and enhances exercise performance by activating critical metabolic pathways at the cellular level.
10mg
Therapeutic Dose
SC/IM
Administration
3-7x
Weekly Dosing
4-12
Week Protocols
Available Dosing
Premium pharmaceutical-grade MOTS-c peptide designed for optimal cellular energy production and metabolic enhancement through targeted mitochondrial optimization.
Standard therapeutic dosage
Ideal For
Individuals seeking enhanced metabolic function, improved exercise performance, increased cellular energy, optimized glucose metabolism, fat loss support, and healthy aging through mitochondrial optimization.
The Science
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a recently discovered mitochondrial-derived peptide that plays a crucial role in cellular energy metabolism and metabolic homeostasis. This 16-amino acid peptide is encoded within the mitochondrial genome and represents a novel class of signaling molecules that communicate between mitochondria and the nucleus to regulate whole-body metabolism.
MOTS-c functions as a powerful metabolic regulator by activating AMPK (AMP-activated protein kinase), a master metabolic switch that enhances glucose uptake, promotes fat oxidation, and improves insulin sensitivity. By optimizing mitochondrial function, MOTS-c increases cellular energy production (ATP), reduces oxidative stress, and supports metabolic flexibility—the ability to efficiently switch between burning carbohydrates and fats for fuel.
Research demonstrates that MOTS-c levels decline with age, contributing to age-related metabolic dysfunction and decreased cellular energy. Supplementation with MOTS-c has shown remarkable potential for improving exercise performance, enhancing recovery, supporting healthy weight management, regulating blood sugar levels, and promoting longevity by restoring youthful mitochondrial function. This makes MOTS-c particularly valuable for individuals seeking to optimize metabolic health, enhance athletic performance, support healthy aging, or address metabolic concerns such as insulin resistance and metabolic syndrome.
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How It Works
MOTS-c enhances cellular metabolism through targeted activation of energy-regulating pathways, improving mitochondrial efficiency and metabolic flexibility for superior energy production and metabolic health.
Activates AMPK signaling to enhance glucose uptake, promote fat oxidation, and improve cellular energy metabolism, acting as a metabolic master switch for optimal energy balance.
Improves insulin sensitivity and glucose metabolism while promoting metabolic flexibility, enabling efficient fuel utilization and supporting healthy blood sugar regulation.
Enhances mitochondrial efficiency and ATP production while reducing oxidative stress, supporting cellular energy generation and protecting against age-related mitochondrial decline.
Clinical Benefits
Optimizes mitochondrial ATP production for increased cellular energy, reducing fatigue and enhancing overall vitality and physical performance capacity.
Enhances endurance, strength, and recovery by optimizing energy metabolism and reducing exercise-induced fatigue for superior athletic performance and training adaptations.
Improves insulin sensitivity, glucose metabolism, and metabolic flexibility, supporting healthy blood sugar regulation and efficient nutrient utilization.
Promotes fat oxidation and healthy weight management by enhancing metabolic rate and improving the body’s ability to utilize fat as fuel.
Counteracts age-related metabolic decline by restoring mitochondrial function, supporting longevity, and promoting cellular health throughout the aging process.
Supports cardiovascular function and metabolic health by improving vascular function, reducing oxidative stress, and enhancing overall cardio-metabolic resilience.
Your Journey
Our medical team guides you through every step—from initial consultation to ongoing optimization.
Comprehensive metabolic evaluation including health history, fitness goals, and current metabolic function to determine candidacy.
Complete metabolic panel, glucose tolerance assessment, and baseline labs to establish your metabolic profile and track improvements.
Receive personalized MOTS-c dosing regimen tailored to your metabolic goals, activity level, and therapeutic objectives.
Regular follow-ups with metabolic testing, performance tracking, and protocol optimization to maximize results and ensure safety.
Safety & Candidacy
MOTS-c is a naturally occurring mitochondrial peptide with an excellent safety profile. Our medical team performs comprehensive metabolic assessments to ensure appropriate candidacy and optimal dosing for your individual needs.
100%
Naturally occurring mitochondrial peptide bioidentical to human MOTS-c
10+
Years of research validating safety and metabolic benefits
Questions
MOTS-c is a mitochondrial-derived peptide that regulates cellular energy metabolism by activating AMPK, a master metabolic switch. It enhances glucose uptake, promotes fat oxidation, improves insulin sensitivity, and optimizes mitochondrial function for increased cellular energy production. MOTS-c acts as a signaling molecule that communicates between mitochondria and the nucleus to regulate whole-body metabolism, supporting metabolic health, exercise performance, and healthy aging.
MOTS-c provides comprehensive metabolic benefits including enhanced cellular energy and reduced fatigue, improved exercise performance and endurance, better insulin sensitivity and glucose metabolism, support for healthy weight management and fat loss, increased metabolic flexibility, enhanced recovery from exercise, and protection against age-related metabolic decline. Many users also report improved mental clarity, sustained energy throughout the day, and better overall vitality. Clinical research supports its role in optimizing metabolic health and promoting longevity.
MOTS-c is administered via subcutaneous or intramuscular injection, typically 3-7 times per week depending on individual goals and response. The standard therapeutic dose is 10mg per injection, though dosing is personalized based on your metabolic profile, activity level, and treatment objectives. Most protocols run for 4-12 weeks, with some individuals benefiting from ongoing use or periodic cycles. Your BHRC physician will determine the optimal dosing schedule and duration for your specific needs.
Many individuals notice increased energy and improved exercise performance within the first 1-2 weeks of consistent use. Metabolic improvements such as enhanced insulin sensitivity and better glucose regulation typically become apparent within 2-4 weeks. More significant changes in body composition, endurance, and metabolic markers generally develop over 4-8 weeks of therapy. For optimal results in metabolic optimization and longevity support, protocols of 8-12 weeks are recommended, with benefits often sustained beyond the treatment period.
MOTS-c has an excellent safety profile with minimal reported side effects. Occasional mild injection site reactions may occur. Unlike anabolic compounds, MOTS-c does not affect hormonal balance and does not require post-cycle therapy. However, individuals with active metabolic disorders, certain chronic conditions, or those taking medications for diabetes should consult with their physician before starting therapy. Comprehensive medical evaluation and baseline metabolic testing ensure safe and appropriate use. There are no known significant drug interactions, but full medication disclosure is essential during consultation.
Yes, MOTS-c can be safely combined with other peptide therapies, hormone optimization, nutritional interventions, and exercise programs. Many patients stack MOTS-c with NAD+ for enhanced cellular energy and longevity benefits, with CJC-1295/Ipamorelin for body composition optimization, or as part of comprehensive metabolic health protocols. It’s also compatible with conventional medications and supplements, though your BHRC physician will review all current treatments to design an integrated protocol optimized for your metabolic goals and health objectives.
MOTS-c therapy is typically not covered by insurance as it’s considered preventive and regenerative medicine focused on metabolic optimization and longevity. BHRC offers transparent pricing and flexible payment options to make this innovative metabolic therapy accessible. Many patients find the investment worthwhile given the comprehensive benefits for energy, performance, metabolic health, and healthy aging. Our team can provide detailed cost information and discuss payment plans during your consultation.
Get Started
Schedule a consultation with our medical team to learn if MOTS-c peptide therapy is right for your wellness journey.
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. MOTS-c is provided for metabolic optimization and wellness purposes under physician supervision. Individual results may vary. A consultation with our medical team and baseline laboratory testing are required to determine if this therapy is appropriate for you.
