In deciding to use a medicine, the risks of taking medication must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or other medicines. Also, tell your healthcare professional if you have allergies to foods, dyes, preservatives, or animals. For nonprescription products, read the label or package ingredients carefully.
Pediatric
The use of progesterone is not indicated in children. Safety and efficacy have not been established.
Geriatric
Although appropriate studies on the relationship of age to the effects of progesterone have not been performed in the geriatric population, no geriatric-specific problems have been documented. However, elderly patients are more likely to have breast cancer, stroke, or dementia, which may require caution in patients receiving progesterone.
Breastfeeding
Studies in women suggest that this medication poses minimal risk to the infant during breastfeeding.
Drug Interactions
Although certain medicines should not be used together, in other cases, two different treatments may be used together even if an interaction occurs. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When taking this medicine, your healthcare professional must know if you are taking any of the medicines listed below. The following interactions have been selected based on their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended but may be required in some cases. If both medications are prescribed, your doctor may change the dose or how often you use one or both medicines.
- Abametapir
- Conivaptan
- Eslicarbazepine Acetate
- Fedratinib
- Fexinidazole
- Fosnetupitant
- Netupitant
Other Interactions
Certain medicines should not be used at or around the time of eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Abnormal or unusual vaginal bleeding or
- Allergy to peanuts or peanut oil or
- Blood clots (e.g., deep vein thrombosis, pulmonary embolism), active or history of or
- Breast cancer, known, suspected, or a history of or
- Heart attack, active or history of or
- Liver disease or
- Stroke, active, or history of—Should not be used in patients with these conditions.
- Asthma or
- Diabetes or
- Edema (fluid retention or body swelling) or
- Endometriosis or
- Epilepsy (seizures) or
- Heart disease or
- Hypercalcemia (high calcium in the blood) or
- Hypercholesterolemia (high cholesterol in the blood) or
- Hypertension (high blood pressure) or
- Kidney disease or
- Migraine headache or
- Systemic lupus erythematosus (SLE) or
- Thyroid problems—Use with caution. This may make these conditions worse.
Source: MayoClinic
