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Injectables · Calcium hydroxylapatite biostimulator

Radiesse Injections

Radiesse by Merz Aesthetics adds support the day it is injected, then helps your skin build its own collagen over the months that follow. $700 to $900 a syringe at BHRC.

FDA approved2006, hands 2015
ResultsVisible the same day
LastsUp to 2 years, per Merz
  • From $700 a syringe, real prices for every clinic below
  • Volume on the day, then collagen and elastin over months
  • FDA approved for smile lines and facial folds, the backs of the hands, the jawline (Radiesse (+)) and chest wrinkles (diluted)
  • Not reversible, so it is planned conservatively by licensed injectors

Radiesse cost at BHRC

From

Per syringe

$700per syringe

$700 to $900 depending on clinic

    Book a Consultation

    New clients save 15% on a first single-syringe treatment at our corporate clinics.

    The new-client offer applies to standard per-syringe pricing at West LA, West Hollywood, Valencia, Westlake Village, Downtown Summerlin and Paradise Valley, not to packages. Henderson offers a Beauty Bank member price; Houston prices separately. Your clinic confirms your price before treatment.

    Financing available

    Pay over time with the same providers we use in center. Checking your options does not affect your credit score.

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    4 interest-free payments
    Illustration of the jawline, an FDA-approved Radiesse (+) area Illustration of the smile-line area Illustration of the backs of the hands Illustration of the chest (décolleté) Illustration of the cheek and mid-face

    Radiesse · Jawline

    In short

    Radiesse is an FDA-approved injectable made of calcium hydroxylapatite microspheres in a soft gel. It adds volume the day it is injected, then helps your skin build new collagen and elastin over the following months, and Merz reports results lasting up to two years. Unlike hyaluronic acid filler, it cannot be dissolved, so it is placed carefully and conservatively. At Beverly Hills Rejuvenation Center Radiesse costs $700 to $900 a syringe depending on the clinic, and every treatment is performed by a licensed medical provider.

    What Radiesse is, and how it works

    Radiesse is made of tiny calcium hydroxylapatite microspheres suspended in a smooth gel of water, glycerin and cellulose. When it is injected beneath the skin, the gel gives support straight away, which is why Merz says the restored volume and smoothing are visible immediately. Over the following months the gel is absorbed and the microspheres act as a scaffold that prompts your skin to make new collagen and elastin. That combination, filler on the day and biostimulator afterwards, is what sets it apart from both hyaluronic acid filler and Sculptra.

    It is firmer than most hyaluronic acid gels and it is not hyaluronic acid, so the enzyme used to dissolve those fillers does not break it down. That is the main trade-off: Radiesse is planned conservatively and placed deep, because there is no undo.

    Radiesse has a long FDA history. It was approved in 2006 for moderate to severe facial wrinkles and folds such as smile lines, and for facial fat loss in people with HIV. The backs of the hands were added in 2015. Radiesse (+), the version mixed with lidocaine, was approved for loss of jawline contour in adults over 21 in 2021. In March 2026 the FDA approved Radiesse diluted 1:2 with saline for chest (décolleté) wrinkles in adults 22 and over. Other uses, such as the neck, arms, abdomen or buttocks, are off-label, and your provider should say so.

    A BHRC injector discussing a Radiesse plan with a patient

    Units and cost

    How many syringes of Radiesse you need

    There is no official syringes-per-area chart. This is what the FDA-reviewed studies used, and what that means for a plan.

    AreaWhat the label studies usedCost at BHRC
    Smile lines and facial folds, FDA approved 2006About 1.2 mL per fold on average in the original study; a syringe is 1.5 mL$700 to $900 a syringe
    Jawline, Radiesse (+), FDA approved 2021Treatment of both sides of the jaw, with an optional touch-up at 4 weeksPlanned at consultation
    Backs of the hands, FDA approved 2015Up to 3 cc (two syringes) per hand per session; more than that was not studiedOften 1 to 2 syringes per hand
    Chest wrinkles, diluted 1:2, FDA approved 2026One 1.5 mL syringe mixed with 3 mL saline per session, three sessions about six weeks apartQuoted at consultation
    Neck, arms, abdomen, buttocks, off-labelNot part of the FDA studies; planned and priced at consultationQuoted at consultation

    Volumes come from the Radiesse and Radiesse (+) instructions for use and the FDA summary for the 2026 chest approval. Your provider sets the amount for your face or body, and you see the price before treatment.

    Price by clinic

    Radiesse price at each BHRC clinic

    Every price below comes from the clinic's current price list. The middle column shows the new-client or member price where that clinic has one.

    ClinicOffer or member pricePer syringe
    West Hollywood, near Beverly Hills$765 for new clients$900
    West Los Angeles$765 for new clients$900
    Valencia, Santa Clarita$680 for new clients$800
    Westlake Village, Thousand Oaks$680 for new clients$800
    Downtown Summerlin, Las Vegas$765 for new clients$900
    Henderson$560 Beauty Bank member price$700
    Paradise Valley, Scottsdale$765 for new clients$900
    Houston CityCentreNo new-client offer listed$800
    Houston River OaksNo new-client offer listed$800

    New clients save 15% on a first single-syringe treatment at the regular price at West LA, West Hollywood, Valencia, Westlake Village, Downtown Summerlin and Paradise Valley. Radiesse earns points with Merz's Xperience+ rewards program. Financing is available through Cherry, CareCredit and others.

    Before you book

    Is Radiesse reversible, and can it migrate?

    The two questions people search most about Radiesse, answered from the label.

    It cannot be dissolved

    Hyaluronic acid filler can be broken down with an enzyme called hyaluronidase. Radiesse is calcium hydroxylapatite in a cellulose gel, so that enzyme does not dissolve it, and the Radiesse labeling describes no agent that reverses it. Researchers have tested sodium thiosulfate as a possible reversal agent, but a 2020 preclinical study found no sign that it broke down the microspheres. Treat Radiesse as a commitment until your body absorbs it.

    Why that changes how it is injected

    The label tells injectors not to overfill, because the area keeps improving for several weeks as the collagen response develops. Good Radiesse treatment is deliberately conservative, placed deep, and topped up later if needed rather than all at once. If you have never had filler, a reversible hyaluronic acid filler is often the sensible first step.

    Can Radiesse migrate?

    It is uncommon, but it is not impossible. The FDA lists migration, movement of filler away from where it was injected, among the rare risks reported for dermal fillers, and Merz's post-marketing list for Radiesse includes product displacement or migration. Correct depth, conservative volumes and an injector who knows the anatomy are what keep it where it was placed.

    It shows up on scans

    The microspheres are visible on CT scans and may show on plain X-rays. That is expected; tell your doctors and radiologists that you have had Radiesse. In a study of 58 patients it did not hide abnormal tissue or look like a tumor on CT. Read more in is Radiesse reversible.

    Skin quality

    Hyperdilute Radiesse

    The same product, mixed with more saline so it spreads thinly and works on skin quality rather than volume.

    What it is

    Merz describes hyperdiluted Radiesse as Radiesse mixed with a higher volume of sterile saline so it can be spread thinly over a larger area. It gives little volume and works mainly by prompting collagen, which is why it is used for crepey skin rather than to fill a line.

    What is FDA approved

    Since March 2026, Radiesse diluted 1:2 with saline is FDA approved for wrinkles of the chest (décolleté) in adults 22 and over. In the study, people had three sessions about six weeks apart, and 71% had at least a one-point improvement at 24 weeks, compared with 6% of untreated people. The décolleté indication requires Merz's dedicated training, so ask your clinic who offers it.

    What is off-label

    Diluted Radiesse on the face for skin quality, the neck, upper arms, abdomen, thighs or buttocks is off-label. These uses appear in expert consensus papers, but they were not part of the FDA review. Note that the FDA recommends against injecting fillers into the neck. Read the full hyperdilute Radiesse guide.

    Body

    Radiesse for the buttocks and BBL

    It is off-label, and the FDA advises against it

    Radiesse's FDA approvals cover the face, the backs of the hands, the jawline and the chest. Buttock treatment is off-label, and the FDA's dermal filler guidance recommends against using any injectable filler to increase the size of the buttocks. You should know that before you decide.

    Where BHRC offers it

    Some patients still choose a non-surgical shape treatment after weighing that. BHRC offers an Instant BBL that combines Sculptra, Radiesse and filler at West Hollywood, West LA, Valencia, Westlake Village, Downtown Summerlin and Paradise Valley. It uses far more product than the face, so it is always planned and priced at consultation.

    Safety

    Radiesse side effects and who should not have it

    Common, short-term effects

    Bruising, redness, swelling, tenderness, itching and small lumps at injection sites, mostly settling within a week. After jawline treatment some people have temporary difficulty chewing. Keep the area out of strong sun and heat for about a day.

    Lumps and nodules

    Firm bumps can occur. In the hand study, 12% of people reported nodules, bumps or lumps, which can last up to a year. Radiesse is not used in the lips: its safety there has not been established, and nodules have been reported.

    Who should not have Radiesse

    Anyone with severe allergies or a history of anaphylaxis, an allergy to its ingredients (or to lidocaine, for Radiesse (+)), or a bleeding disorder. Treatment is deferred if there is an active skin infection or inflammation in the area. It has not been studied in pregnancy, breastfeeding, under 18, or in people prone to keloid scars.

    Serious but rare

    Any injectable can, rarely, enter a blood vessel and block it, which can damage skin or affect vision. This is why Radiesse should only be injected by a trained, licensed provider who knows the anatomy and stops at once if anything changes.

    Rewards

    Radiesse earns Xperience+ rewards

    Xperience+ by Merz Aesthetics

    Radiesse is part of Xperience+, Merz Aesthetics' free rewards program, which also covers Xeomin, Belotero and Ultherapy. BHRC accepts Xperience+.

    How points work

    Merz's site says you earn 200 points for each Radiesse syringe at participating providers, and every 100 points is worth $10 toward a future qualifying treatment. Points expire 12 months after they are earned, and Merz sets the program terms. Join at xperiencemerz.com before your visit.

    Treatment areas

    Where Radiesse is used

    How it works

    What happens at a Radiesse appointment

    Usually 30 to 45 minutes, including the time to agree your plan.

    Consultation and plan. Your provider assesses volume, structure and skin quality, agrees the areas, and tells you which are on-label and how many syringes the plan needs.

    Preparation. The skin is cleansed. Radiesse (+) already contains lidocaine; standard Radiesse can be mixed with it, and topical numbing is offered.

    Injection. Small amounts are placed deep beneath the skin with a fine needle or blunt cannula, then gently molded so the contour is smooth.

    Check and follow-up. You see the immediate support before you leave. Your provider reviews the result once swelling settles and plans any top-up conservatively.

    Which product

    Radiesse, Sculptra or hyaluronic acid filler

    How each one works, how quickly and how long.

    Radiesse, Sculptra and hyaluronic acid filler compared
    Radiesse

    Starts working: Immediate, then builds. Lasts: Up to 2 years, per Merz. Calcium hydroxylapatite: volume on the day plus collagen afterwards. Often chosen for jawline, cheeks, folds and hands. $700 to $900 a syringe at BHRC. Cannot be dissolved.

    Sculptra

    Starts working: From about 1 month, builds over sessions. Lasts: Up to 2 years, per Galderma. Poly-L-lactic acid: almost entirely collagen stimulation, over two to three sessions. Priced per vial. Cannot be dissolved.

    Restylane and other HA fillers

    Starts working: Immediate, settles in 2 weeks. Lasts: About 6 to 18 months by product. Hyaluronic acid gel: instant, adjustable, and can be dissolved with hyaluronidase. The usual choice for lips and first-time patients.

    Good to know

    What to know about each area

    Approved areas first, then off-label uses, then the places Radiesse is not used.

    A BHRC injector administering a biostimulator treatment
    Smile lines, marionette lines and cheeks

    Smile lines and other facial folds are covered by the original approval for moderate to severe facial wrinkles and folds. Cheek and mid-face volume is a common use, but it is not a separate US indication, so your provider will discuss it at consultation.

    Jawline

    Radiesse (+) is approved to improve moderate to severe loss of jawline contour in adults over 21. In the study, 76% of treated people improved at 12 weeks, compared with 9% of untreated people. Chewing can feel different for a short time.

    Backs of the hands

    Approved since 2015 to restore volume so tendons and veins show less. Up to two syringes per hand per session were studied.

    Chest, diluted

    Approved in 2026 for décolleté wrinkles when diluted 1:2 with saline, in a series of sessions. Not injected over or including breast tissue.

    Not the lips or eyes

    Safety in the lips and around the eyes has not been established, and nodules have been reported in lips. For lips, a hyaluronic acid filler such as Restylane Kysse is the right tool.

    Aftercare

    Aftercare after Radiesse

    Simple, and mostly about the first day.

    A BHRC provider reviewing aftercare with a patient
    The first 24 hours

    Expect some swelling, tenderness and possibly bruising. The label advises keeping the area out of strong sun and heat, including saunas, for about 24 hours or until swelling and redness settle.

    Hands and jawline

    Hands can swell and everyday tasks can feel awkward for a few days. After jawline treatment, chewing may feel different for a short time. Both are expected and temporary.

    Do not judge it early

    What you see on day one includes swelling. Judge the result after about two weeks, and remember collagen keeps building for months.

    Laser and peels

    Tell any provider who plans laser, peels or similar treatments in the same area that you have had Radiesse, because those can trigger inflammation at the implant site.

    Aftercare

    What to use at home afterwards.

    Your result lasts longer when what you use at home is doing the same work. This is the routine our providers start most patients on, dispensed through the practice. Not sure it is right for your skin? Take the skin quiz, or ask your provider to build one around the treatment you are having.

    The full routine, $463.

    All four steps together. Dispensed by the practice and shipped to you, or picked up at any of our 22 centers.

    Is it for you

    Who Radiesse suits

    Radiesse suits people who want visible support now and longer-lasting improvement in skin quality, and who are comfortable with a treatment that cannot be dissolved.

    Radiesse may suit you if you

    • Have deeper smile lines, marionette lines or mid-face volume loss
    • Want a sharper jaw border without surgery
    • Notice thinning on the backs of your hands
    • Have crepey chest skin and prefer a series of sessions
    • Want results that last longer than many hyaluronic acid fillers

    Raise these at consultation

    • Severe allergies, anaphylaxis, or a lidocaine allergy
    • A bleeding disorder or blood-thinning medication
    • A history of keloids or raised scars
    • Pregnancy or breastfeeding
    • Wanting lip filler, or a first filler you can reverse, which suits hyaluronic acid better

    These are things to discuss, not automatic disqualifications, except the contraindications in the Radiesse labeling (severe allergies, ingredient allergy, bleeding disorders).

    Your timeline

    Radiesse results timeline

    Some change on the day, more over the months after.

    1. Day 0Immediate supportThe gel restores volume and smooths lines straight away.
    2. Days 1 to 7Swelling settlesBruising and tenderness fade; most reactions last under a week.
    3. Week 2 to 4True result showsYour provider reviews the contour and plans any conservative top-up.
    4. Months 2 to 12Collagen buildsThe microspheres prompt new collagen and elastin as the gel is absorbed.
    5. Up to 2 yearsResults lastMerz reports results lasting up to two years; how long depends on the area.

    Frequently asked

    Radiesse questions, answered

    What is Radiesse?

    Radiesse is an FDA-approved injectable by Merz Aesthetics made of calcium hydroxylapatite microspheres in a gel. It adds volume the day it is injected and then stimulates collagen, so it is both a filler and a biostimulator. It is approved for facial wrinkles and folds, the backs of the hands, the jawline (Radiesse (+)) and, diluted, chest wrinkles.

    How does Radiesse work?

    The gel gives immediate support. As the gel is absorbed over the following months, the microspheres act as a scaffold and your skin builds new collagen and elastin around them, which is why skin quality keeps improving after the first few weeks.

    How much does Radiesse cost?

    At BHRC, Radiesse is $700 a syringe in Henderson ($560 for Beauty Bank members), $800 in Valencia, Westlake Village and Houston, and $900 in West Hollywood, West LA, Downtown Summerlin and Paradise Valley. New clients save 15% on a first single syringe at six clinics. See the price by clinic table.

    How many syringes of Radiesse will I need?

    It depends on the area. In the original smile-line study about 1.2 mL was used per fold, a little less than one 1.5 mL syringe. Hands were studied at up to two syringes per hand per session. Your provider confirms the number before treatment.

    How long does Radiesse last?

    Merz reports results lasting up to two years. How long yours last depends on the area, the amount used and your own collagen response, and many people plan a top-up rather than waiting for it to fade completely.

    Is Radiesse reversible? Can it be dissolved?

    No. Radiesse is not hyaluronic acid, so hyaluronidase, the enzyme that dissolves hyaluronic acid filler, does not break it down, and no reversal agent is approved. That is why it is placed conservatively and why first-time filler patients often start with hyaluronic acid.

    Does Radiesse migrate?

    Migration is uncommon but possible. The FDA lists it among rare filler risks and Merz's post-marketing reports include product displacement. Correct depth, conservative volumes and an experienced injector keep it in place.

    Is Radiesse hyaluronic acid? Is it a filler?

    It is not hyaluronic acid. It is calcium hydroxylapatite in a cellulose gel. It is FDA approved as a dermal filler and Merz also calls it a biostimulator, because it prompts collagen after the initial volume.

    What is hyperdilute Radiesse?

    Radiesse mixed with extra saline so it spreads thinly and improves skin quality rather than adding volume. Diluted 1:2, it has been FDA approved for chest wrinkles since March 2026; other diluted uses are off-label. See our hyperdilute Radiesse guide.

    Is Radiesse FDA approved for the jawline and hands?

    Yes. Radiesse has been approved for the backs of the hands since 2015, and Radiesse (+) is approved to improve moderate to severe loss of jawline contour in adults over 21.

    Can Radiesse be used in the lips?

    No. Its safety and effectiveness in the lips have not been established, and nodules have been reported there. Hyaluronic acid fillers such as Restylane Kysse are used for lips.

    Can Radiesse be used for a butt lift or BBL?

    Only off-label, and the FDA recommends against using fillers to increase buttock size. BHRC's Instant BBL combines Sculptra, Radiesse and filler at six clinics, and your provider explains the risks, products and price at consultation.

    Radiesse or Sculptra: which should I choose?

    Radiesse gives support the same day and then stimulates collagen, and it is often chosen for the jawline, deeper folds and hands. Sculptra works almost entirely through collagen over two to three sessions. Neither can be dissolved. See Sculptra.

    Does Radiesse earn rewards points?

    Yes. Radiesse earns points in Xperience+, Merz Aesthetics' rewards program, which BHRC accepts. Merz's site lists 200 points per syringe, with every 100 points worth $10 toward a future treatment; Merz sets the terms.

    Enhance your results

    Pairs well with Radiesse

    Radiesse supports structure. These handle the lips, expression lines and the skin surface.

    Our team

    The people behind your care.

    The molecule is the same everywhere. Who holds the syringe is not.

    Megan Lafuente, Nurse Practitioner at BHRC West Hollywood

    Nurse Practitioner

    Megan Lafuente

    West Hollywood

    What Megan does

    • Neurotoxins
    • Dermal filler
    • Hormone therapy
    • Peptide protocols
    • Medical weight management
    • Lab work review
    Licensed medical injectors

    Every Radiesse treatment is given by a nurse practitioner, registered nurse, physician assistant or physician trained on the product.

    Real prices, published

    Every clinic's Radiesse price is on this page, taken from that clinic's own price list, and confirmed before you are treated.

    On-label and off-label, said plainly

    We tell you which areas the FDA has reviewed, which are off-label, and when a reversible filler would suit you better.

    Find a center

    Radiesse near you

    All nine BHRC clinics offer Radiesse. Pick your closest for directions, hours and local pricing.

    Start your journey

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    Start your journey

    Plan your Radiesse treatment

    Book a consultation at your nearest clinic. Your provider will assess volume and skin quality, explain which areas are on-label, and confirm the syringes and price before you start.

    Medically reviewed by the BHRC clinical team. Last reviewed November 2026.

    This page is for general information and is not medical advice. Treatment suitability, pricing and results vary by individual and are confirmed at consultation with a licensed provider.