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Injectables

Biological Fillers for Natural Volume & Rejuvenation

Biostimulators do not fill. They provoke your own body into producing collagen, so the change arrives over months and looks like you rather than like treatment. It also cannot be dissolved, which is the trade.

Treatment time30 to 45 minutes
Results lastUp to 2 years
DowntimeSwelling 2 to 3 days
  • $900 a syringe, 3 for $2,400
  • Builds your own collagen over 3 to 6 months
  • Sculptra and Radiesse both carried
  • Not reversible, unlike hyaluronic acid filler

Sculptra and Radiesse cost at BHRC

Single syringe

$900per syringe

Sculptra or Radiesse

    Book a Consultation
    Save $300

    3-Syringe Package

    $900$800per syringe

    3 syringes for $2,400

    • The 3-vial series most facial volume loss actually needs
    Book a Consultation

    New clients save 15% on your first treatment.

    Both products are $900 a syringe, and three is the usual Sculptra series for meaningful facial volume loss, spaced four to six weeks apart. Because biostimulators build gradually, the vial count is planned at consultation rather than added to as you go. The new-client discount applies to standard per-syringe pricing.

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    Close-up of restored mid-face volume after Sculptra at BHRC Close-up of filled temples after biostimulator treatment at BHRC Close-up of a defined jawline after Radiesse at BHRC Close-up of softened nasolabial folds after Radiesse at BHRC Close-up of the backs of the hands after Radiesse at BHRC Close-up of the decolletage after diluted Sculptra at BHRC

    Biological fillers · Cheeks and mid-face

    In short

    Biological fillers, or biostimulators, are injectables that prompt your own body to produce collagen rather than adding volume directly. Sculptra is poly-L-lactic acid and works almost entirely by stimulation, so the result builds over three to six months across a series. Radiesse is calcium hydroxylapatite and does both: it adds volume on the day and stimulates collagen afterwards. Both are $900 a syringe at BHRC and neither can be dissolved.

    These do not fill. They provoke.

    A hyaluronic acid filler is exactly what it sounds like: a gel that occupies space, so you see the result the moment it is placed and it can be dissolved if you hate it. A biostimulator does something different and slower. Sculptra irritates the tissue just enough that your body responds by laying down collagen around the particles, over weeks and months. You leave looking essentially unchanged, and three months later people say you look well without knowing why. That is the appeal, and the cost of it is that there is no undo button.

    A BHRC injector discussing biostimulator options with a patient

    Units and cost

    What each treats, and what it costs

    By area and product.

    AreaTypical unitsCost
    Overall facial volume lossSculptra, 3 vials$2,400 package
    TemplesSculptra, 1 to 2 vials$900 per syringe
    Cheeks and mid-faceSculptra or Radiesse$900 per syringe
    Jawline definitionRadiesse, 1 to 2 syringes$900 per syringe
    Nasolabial foldsRadiesse, 1 syringe$900 per syringe
    Backs of the handsRadiesse, 1 to 2 syringesfrom $900
    Chest crepinessSculptra, diluted$900 per syringe
    Buttocks (Sculptra BBL)Multiple vialsQuoted at consultation

    Sculptra is usually a series of three vials spaced four to six weeks apart, because collagen takes time and you cannot judge the result between sessions. Radiesse is more often a single syringe per area.

    Treatment areas

    Where we treat

    How it works

    How Biological Fillers Work

    Two different molecules, two different timelines.

    Sculptra is poly-L-lactic acid, a material used in dissolvable sutures for decades. Injected into the deep dermis it triggers a controlled response that lays down new collagen around each particle as the particle itself is absorbed.

    Radiesse is calcium hydroxylapatite microspheres in a gel carrier. The gel adds volume immediately, and as it is absorbed the microspheres provide a scaffold that new collagen forms along.

    Both are building tissue rather than occupying space, which is why the result is judged at three months rather than two weeks, and why neither can be dissolved the way hyaluronic acid can.

    Which product

    Sculptra vs Radiesse vs hyaluronic acid filler

    Three products, three completely different propositions.

    Sculptra and Radiesse compared at BHRC
    Sculptra

    Starts working: 6 to 12 weeks. Lasts: Up to 2 years. Pure stimulation. Nothing much happens for weeks, then collagen builds gradually. Best for overall volume loss across the face rather than one line. Series of three, $900 a vial. Cannot be dissolved.

    Radiesse

    Starts working: Immediate, then builds. Lasts: 12 to 18 months. Volume on the day plus collagen afterwards. The middle option, and the usual choice for jawline and hands. $900 a syringe. Also cannot be dissolved.

    HA filler (Juvederm, Restylane)

    Starts working: Immediate, settles 2 weeks. Lasts: 6 months to 2 years. A gel that occupies space. Instant, controllable and REVERSIBLE with hyaluronidase, which makes it the sensible first experience of injectables. From $700 a syringe.

    Doing neither yet

    Starts working: n/a. Lasts: n/a. If your face has loosened rather than deflated, volume is the wrong answer and tightening is the right one. Morpheus8 and Ultherapy do that, and we would rather send you there than sell you three vials.

    Good to know

    What Biological Fillers Can Do For You

    And the one thing you should understand before booking.

    A BHRC injector administering a biostimulator treatment
    Restore volume gradually

    Collagen builds over months, so the change is invisible week to week and obvious in photographs. Nobody catches you having had something done.

    Treat the whole face, not one line

    Sculptra suits diffuse volume loss, which is what most ageing actually is, rather than a single fold.

    Fill temples and hollows

    Areas where hyaluronic acid can look obvious and a biostimulator generally does not.

    Define a jawline

    Radiesse holds its position well, which is why it is often chosen along the jaw border.

    Treat the backs of the hands

    One of very few products with an established use there, and hands give age away long before faces do.

    Improve skin quality, not just volume

    New collagen thickens the skin itself, which is a different effect from filling underneath it.

    ⚠️ It cannot be dissolved

    Hyaluronic acid can be reversed with hyaluronidase. Sculptra and Radiesse cannot. That is the single most important difference and it is why we usually start people on HA.

    Aftercare

    Aftercare, and the long wait

    Including the massage nobody remembers to do.

    A BHRC injector demonstrating post-treatment massage
    The first 24 hours

    Swelling and possible bruising at injection points. What you see now is the water in the product, not the result.

    Massage, for Sculptra

    Five minutes, five times a day, for five days. It matters: it distributes the particles evenly and reduces the risk of nodules. This is the most commonly skipped instruction in aesthetics.

    Week 1

    Initial swelling resolves and the face returns to how it looked before. This is expected and is not the treatment failing.

    Weeks 6 to 12

    Collagen begins to show. The first genuine change.

    Months 3 to 6

    The full result of a series. Comparison photographs are the only reliable way to see it, because it arrived too slowly to notice.

    Between vials

    Four to six weeks, so each is judged before the next is planned.

    Up to 2 years

    Then a top-up, usually needing fewer vials than the first course.

    Aftercare

    What to use at home afterwards.

    Your result lasts longer when what you use at home is doing the same work. This is the routine our providers start most patients on, dispensed through the practice. Not sure it is right for your skin? Take the skin quiz, or ask your provider to build one around the treatment you are having.

    The full routine, $463.

    All four steps together. Dispensed by the practice and shipped to you, or picked up at any of our 22 centers.

    Is it for you

    Ideal candidates for Biological fillers

    Fillers Biological fillers are suitable for a wide range of adults seeking to enhance their appearance naturally.

    You may be an ideal candidate if you have

    • Notice loss of facial volume with aging
    • Want to smooth lines, wrinkles, or folds
    • Desire fuller, more defined lips
    • Seek enhanced cheek or jawline contours
    • Have hollowing under the eyes or temples
    • Want to correct facial asymmetry
    • Desire a refreshed, youthful appearance
    • Prefer non-surgical facial rejuvenation

    It may require special consideration if you

    • Are currently pregnant or breastfeeding
    • Have active skin infections or inflammation
    • Have a history of severe allergies or anaphylaxis
    • Are prone to keloid scarring
    • Have autoimmune conditions affecting skin
    • Are taking blood thinners (may increase bruising)
    • Have unrealistic expectations about results

    During your consultation your provider will assess you and review your medical history to make sure this treatment is safe and appropriate for you.

    Your timeline

    What happens, and when

    A slow treatment, deliberately.

    1. ConsultationAssessmentYour injector establishes whether you have lost volume or lost support, because only one of those is treated with this.
    2. Treatment dayNumbingTopical numbing, then injection into the deep dermis across the area rather than into a single point.
    3. 30 to 45 minThe treatmentFollowed by massage instructions you should actually follow.
    4. 4 to 6 weeksNext vialThen three to six months for the full result of the series.

    Frequently asked

    Sculptra and Radiesse questions, answered

    What are biological fillers and how do they work?

    Biological fillers are injectable treatments made from biocompatible materials (most commonly hyaluronic acid) that restore volume, smooth wrinkles, and enhance facial contours. Once injected, the filler integrates with your tissue and attracts water molecules, creating natural-looking fullness. They work by replacing volume lost due to aging and stimulating your skin’s own collagen production.

    How long do filler results last?

    Filler longevity depends on the type of filler used and the treatment area. Lip fillers typically last 6-12 months, while cheek and jawline fillers can last 12-24 months. Areas with more movement (like lips) metabolize filler faster. Your provider will discuss expected duration based on your specific treatment plan during your consultation. Are dermal fillers safe?

    What are the side effects?

    FDA-approved dermal fillers have an excellent safety profile when administered by trained professionals. Common side effects include temporary swelling, redness, bruising, and tenderness at injection sites—these typically resolve within 1-2 weeks. Serious complications are rare but can include infection or vascular occlusion, which is why choosing an experienced injector is crucial.

    Does getting filler hurt?

    Most patients describe filler injections as mild discomfort rather than pain. We apply topical numbing cream before treatment, and most fillers contain lidocaine to minimize sensation during injection. Using cannulas (blunt-tipped needles) in certain areas also reduces discomfort. Most patients are pleasantly surprised by how comfortable the experience is.

    Can filler be reversed if I don’t like the results?

    Yes! Hyaluronic acid fillers can be dissolved with an enzyme called hyaluronidase if you’re unhappy with your results or experience complications. This is one of the major advantages of HA fillers—they’re completely reversible. The dissolving process works within 24-48 hours, returning the treated area to its pre-treatment state.

    What’s the difference between Botox and fillers?

    Botox and fillers address different concerns. Botox relaxes muscles to smooth dynamic wrinkles (those caused by movement, like forehead lines and crow’s feet). Fillers add volume to smooth static wrinkles, restore lost volume, and enhance facial contours. Many patients combine both treatments for comprehensive facial rejuvenation—Botox for the upper face and fillers for the mid and lower face.

    How much filler will I need?

    The amount of filler needed varies based on your goals and facial anatomy. Lip enhancement typically requires 0.5-1 syringe, while cheek augmentation may need 1-2 syringes per side. Full-face rejuvenation often requires 3-6 syringes. During your consultation, your provider will assess your face and recommend the appropriate amount to achieve natural-looking results.

    What should I avoid before and after filler treatment?

    Before treatment, avoid blood thinners, alcohol, and supplements like fish oil, vitamin E, and ginkgo biloba for 1 week to minimize bruising. After treatment, avoid strenuous exercise, alcohol, and excessive heat (saunas, hot yoga) for 24-48 hours. Don’t massage the treated areas unless instructed, and sleep elevated the first night to reduce swelling. Individual results may vary. Dermal filler treatments are medical procedures that should only be performed by qualified, licensed professionals. Consult with our medical professionals to determine if filler treatment is right for you. The content on this page is for informational purposes only and does not constitute medical advice. Patient testimonials reflect individual experiences and results may vary. Before and after photos represent possible results; individual outcomes depend on numerous factors including skin type, age, and treatment area.

    Enhance your results

    Complementary Treatments

    What pairs well with neurotoxin.

    Our team

    The people behind your care.

    The molecule is the same everywhere. Who holds the syringe is not.

    Megan Lafuente, Nurse Practitioner at BHRC West Hollywood

    Nurse Practitioner

    Megan Lafuente

    West Hollywood

    What Megan does

    • Neurotoxins
    • Dermal filler
    • Hormone therapy
    • Peptide protocols
    • Medical weight management
    • Lab work review
    We usually start you on the reversible one

    Sculptra and Radiesse cannot be dissolved. If you have not had injectables before, hyaluronic acid is the sensible first step and we will say so.

    Both biostimulators carried

    Sculptra and Radiesse behave differently. Having both means the choice is clinical rather than whatever is in the fridge.

    The price is on the page

    $900 a syringe, $2,400 for the three-vial series. No consultation required to find out.

    We will tell you if it is laxity

    Volume loss and loss of support look similar and are treated completely differently. Filling a face that has dropped makes it heavier, not younger.

    Massage instructions you will actually get

    Five minutes, five times a day, five days after Sculptra. It reduces nodule risk and most clinics mention it once and move on.

    Licensed medical injectors, never technicians

    Irreversible products demand more of the injector, not less.

    Find a center

    Sculptra and Radiesse near you

    Available at all 22 centers. Pick your closest for directions, hours and local pricing.

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    Start your journey

    Ready to Build Rather Than Fill?

    Schedule your complimentary consultation. Your injector will tell you whether a biostimulator, a hyaluronic acid filler, or a tightening treatment is the honest answer for what you are seeing.

    Medically reviewed by the BHRC clinical team. Last reviewed August 2026.

    This page is for general information and is not medical advice. Treatment suitability, pricing and results vary by individual and are confirmed at consultation with a licensed provider.