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Injectables

Rejuran Skin Booster

Salmon DNA polynucleotides. It sounds strange and it is one of the most interesting skin-quality treatments to arrive in years.

Treatment time30 to 45 minutes
Course3 to 4 sessions
Downtime1 to 3 days of bumps
  • Polynucleotides from purified salmon DNA
  • Repairs skin quality, adds no volume
  • A course of 3 to 4 sessions
  • Also available through microneedling

Rejuran cost at BHRC

Single session

Call for pricing

Injection or with microneedling

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    Recommended

    Course of 3 to 4

    Call for pricing

    The protocol it is designed around

    • Sessions 2 to 4 weeks apart, then maintenance
    Request a Consultation

    New clients save 15% on your first treatment.

    Pricing depends on the area and on whether it is injected or infused through microneedling, so it is quoted by phone rather than listed. Send the form below and we will come back with current pricing. Ask about the course price rather than the single session, because a single Rejuran session will not show you what the treatment does.

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    Rejuran full face treatment at BHRC Rejuran under-eye treatment at BHRC Rejuran cheek treatment at BHRC Rejuran neck treatment at BHRC Rejuran for acne scarring at BHRC Rejuran with microneedling at BHRC

    Rejuran · Full face

    In short

    Rejuran is a skin booster made from polynucleotides, fragments of DNA purified from salmon. Injected into the skin in a series of small microinjections, they act as a repair signal, improving elasticity, hydration and overall skin quality over a course of three to four sessions. It is not a dermal filler and adds no volume. At BHRC it is also available as a booster infused through microneedling channels.

    Salmon DNA, and why that is not as odd as it sounds

    Polynucleotides are short chains of DNA, and the ones used in Rejuran are purified from salmon because salmon DNA is structurally very similar to human DNA and is well tolerated. Injected into skin, they do not add volume or fill anything. They act as a signal, prompting fibroblasts toward repair: better hydration, better elasticity and better overall skin quality. It is a genuinely different mechanism from filler, which adds material, and from neurotoxin, which stops movement. Rejuran is closer in spirit to microneedling or PRP than to anything injected for shape, and like those it works over a course rather than in one visit.

    A BHRC provider discussing Rejuran with a patient

    Units and cost

    Where Rejuran fits against what else we carry

    Skin-quality treatments, side by side.

    AreaTypical unitsCost
    RejuranRepair signalling, elasticityCall for pricing
    SkinviveHydration and glow$350
    PRPYour own growth factorsfrom $950
    Cell FactorAcellular growth factorsfrom $499
    MicroneedlingCollagen via controlled injuryfrom $500
    Dermal fillerVolume and structurefrom $700

    The first five all treat skin quality by different mechanisms and none of them add volume. Only the last one changes facial shape. Which of the five suits you depends on your skin and on whether you are willing to have blood drawn.

    Treatment areas

    Where we treat

    How it works

    How Rejuran Works

    A repair signal, delivered into the skin.

    Polynucleotides are extracted and purified from salmon DNA. The purification is the important part: what is delivered is the nucleotide chain, not salmon protein, which is why allergy is not the concern people assume it would be.

    They are delivered into the dermis, either as a series of small microinjections across the area or infused through microneedling channels while those channels are open.

    In the skin they act as a signalling molecule, supporting fibroblast activity and the skin's own repair processes. The effect is on skin quality, hydration and elasticity rather than on volume or shape.

    Because it works by prompting your own repair rather than by adding material, the change is gradual and cumulative. A course of three to four sessions two to four weeks apart is the protocol; one session is not a trial, it is an incomplete course.

    Which product

    Rejuran vs. the other skin boosters

    Four ways to improve skin quality, honestly compared.

    A BHRC provider comparing skin booster options
    Rejuran

    Starts working: 1 to 3 days of bumps. Lasts: Cumulative over a course. Polynucleotides that act as a repair signal. Best for overall skin quality, elasticity and resilience. Needs a course of three to four. Not a filler and adds no volume.

    Skinvive

    Starts working: 1 to 3 days of bumps. Lasts: About 6 months. $350. Pure hydration and glow, one session, no course. Simpler and more immediate, but it does less: hydration rather than repair.

    PRP

    Starts working: 1 to 2 days. Lasts: Improves over months. From $950. Your own platelets, so nothing foreign is introduced, and it has the longest track record of the four. Requires a blood draw.

    Cell Factor

    Starts working: As base treatment. Lasts: Improves over months. From $499 as a booster. Growth factors with no blood draw. Newer, with less published evidence than PRP.

    Good to know

    What Rejuran Can Do For You

    Skin quality, not facial shape.

    A BHRC provider administering a Rejuran treatment
    Improve elasticity

    The property Rejuran is most associated with, and what distinguishes it from pure hydrators.

    Better overall skin quality

    Resilience and healthy appearance rather than a single fixed problem.

    Hydration from within

    Improved water retention in the dermis.

    Fine lines and crepiness

    Improves from beneath as skin quality improves.

    Under-eye skin

    One of its more popular uses, where the skin is thin and filler is risky.

    ⚠️ Not add volume

    It is not a filler. No cheekbones, no lift, no contour change.

    ⚠️ Not work in one session

    It is a course. Anyone selling you a single Rejuran session as a trial is selling you an incomplete treatment.

    Aftercare

    After Rejuran

    Similar to Skinvive: a bumpy 48 hours, then it settles.

    A BHRC provider finishing a Rejuran treatment
    First few hours

    Small raised bumps at each injection point, expected rather than a complication.

    24 to 72 hours

    The bumps settle as the product disperses.

    Bruising

    Possible, especially under the eyes, where the skin is thinnest.

    Avoid

    Heat, heavy exercise and alcohol for 24 hours.

    Between sessions

    Two to four weeks. The interval matters because the effect is cumulative.

    Through the course

    Change is gradual. Matched-light photographs are the only reliable way to see it.

    Maintenance

    Usually every six to twelve months after the initial course.

    Is it for you

    Who Rejuran suits

    Rejuran suits people focused on skin quality who are willing to commit to a course rather than a single visit.

    Rejuran may suit you if you

    • Want to improve skin elasticity and resilience rather than add volume
    • Have fine lines, crepiness or generally tired-looking skin
    • Are treating thin under-eye skin where filler carries more risk
    • Are happy to commit to a course of three to four sessions
    • Have tried hydrators and want something working on repair rather than water retention
    • Prefer a treatment that works with your own skin biology

    Rejuran may not suit you if you

    • Want more volume, structure or defined cheekbones — that is dermal filler
    • Want a single-visit result, since this is cumulative across a course
    • Have a known fish or seafood allergy — raise it before booking
    • Are pregnant or breastfeeding
    • Have an active skin infection or inflammation in the treatment area

    We also carry Skinvive, PRP and Cell Factor, which treat skin quality by different mechanisms. Your provider will compare them for your skin rather than defaulting to one.

    Your timeline

    What happens, and when

    A course, then maintenance.

    1. ConsultationIs it the right boosterYour provider will compare Rejuran against Skinvive, PRP and Cell Factor for your skin and your tolerance for needles.
    2. Sessions 1 to 42 to 4 weeks apartInjections or infused through microneedling. Small bumps settle within 72 hours.
    3. Through the courseCumulativeGradual improvement in elasticity and skin quality. Photograph in matched light.
    4. 6 to 12 monthsMaintenanceA single session to hold the result.

    Frequently asked

    Rejuran questions, answered

    What is Rejuran made of?

    Polynucleotides, which are short chains of DNA purified from salmon. Salmon DNA is used because it is structurally very similar to human DNA and is well tolerated. What is injected is the purified nucleotide chain rather than salmon protein.

    Is Rejuran a filler?

    No. It adds no volume and will not change your facial shape or contours. It is a skin booster: it acts as a repair signal that improves skin quality, elasticity and hydration. If you want structure or cheekbones, you want a dermal filler instead.

    I have a fish allergy. Can I have Rejuran?

    Raise it with your provider before booking. The polynucleotides are purified, so the salmon proteins that cause fish allergy are not what is being injected, but this is exactly the kind of thing to discuss at consultation rather than read about online. Your provider will review your history properly.

    How much does Rejuran cost at BHRC?

    Pricing depends on the area and on whether it is injected or infused through microneedling, so it is quoted by phone. Call your nearest studio on (310) 912-7271. Ask for the course price rather than the single-session price, since it is designed as a course of three to four.

    How many sessions do I need?

    Three to four, spaced two to four weeks apart, then maintenance every six to twelve months. The effect is cumulative, so a single session will not show you what the treatment does. Budget for the course.

    Rejuran or Skinvive?

    They overlap but are not the same. Skinvive is simpler: one session, $350, pure hydration and glow, lasting about six months. Rejuran is a course aimed at skin repair and elasticity rather than hydration alone. If you want a quick glow, Skinvive. If you want to work on skin quality over time, Rejuran.

    Does it hurt?

    There is some discomfort, since it is a series of small injections into the skin. Topical numbing is applied first. Having it infused through microneedling channels instead of injected is noticeably more comfortable and is a common choice for that reason.

    Is Rejuran FDA-approved?

    Ask your provider about the current regulatory status of the specific product being used, and they will tell you plainly. Polynucleotide treatments are well established in Korea and increasingly used in the US, but the regulatory position differs between countries and we are not going to imply an approval status on a web page.

    Enhance your results

    Complementary Treatments

    What pairs well with neurotoxin.

    Our team

    The people behind your care.

    The molecule is the same everywhere. Who holds the syringe is not.

    Megan Lafuente, Nurse Practitioner at BHRC West Hollywood

    Nurse Practitioner

    Megan Lafuente

    West Hollywood

    What Megan does

    • Neurotoxins
    • Dermal filler
    • Hormone therapy
    • Peptide protocols
    • Medical weight management
    • Lab work review
    We carry four different skin boosters

    Rejuran, Skinvive, PRP and Cell Factor. They work by genuinely different mechanisms, so the recommendation can be about your skin rather than about what we stock.

    We will not call it a filler

    It adds no volume. Selling a skin booster to someone who wants cheekbones is how people end up disappointed and out of pocket.

    We are straight about the regulatory position

    Polynucleotides are well established in Korea and newer in the US. Your provider will tell you the current status of the product being used rather than implying an approval we cannot claim.

    Priced and sold as a course

    Because that is how it works. One session is an incomplete treatment, not a trial.

    Injected or infused, your choice

    Through microneedling channels is more comfortable and treats texture at the same time.

    One protocol across 22 studios

    Standardised training and the same protocols in every location.

    Find a studio

    Rejuran near you

    Available at all 22 studios. Pick your closest for directions, hours and local pricing.

    Start your journey

    Tell us what you are considering and where, and a provider will be in touch.

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    Curious About Polynucleotides?

    Schedule your complimentary consultation. Your provider will tell you whether Rejuran is the right skin booster for you, or whether Skinvive, PRP or Cell Factor would suit you better.

    Medically reviewed by the BHRC clinical team. Last reviewed August 2026.

    This page is for general information and is not medical advice. Treatment suitability, pricing and results vary by individual and are confirmed at consultation with a licensed provider.