Injectables · Neurotoxin
Daxxify is Revance's botulinum toxin for frown lines, the first formulated with a peptide instead of human albumin. Here is what its FDA label says, and where BHRC offers it.
Daxxify earns points in REVA Revance Rewards, and Henderson's Beauty Bank members save 20% on aesthetic services.
Henderson is an independently owned BHRC franchise and sets its own prices. Prices are confirmed before treatment.
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In short
Daxxify (daxibotulinumtoxinA-lanm) is a prescription botulinum toxin type A made by Revance. The FDA approved it in 2022 to temporarily improve moderate to severe frown lines between the brows in adults, at a dose of 40 units in five injections. It is formulated with a 35 amino acid peptide, called RTP004, in place of the human albumin used in other toxins. In its two main trials, 74% of people reached the success measure at week four, and everyone was followed for at least 24 weeks. Daxxify units are not the same as Botox units. At Beverly Hills Rejuvenation Center, Daxxify is offered at our Henderson clinic, sold by the vial and priced at consultation.
Daxxify is daxibotulinumtoxinA-lanm, a botulinum toxin type A made by Revance. It works the same way Botox, Dysport and Xeomin do: it blocks the nerve signal to a small muscle, the muscle relaxes, and the skin over it stops creasing. It does not fill lines that are there at rest because of lost volume; that is a filler question.
What sets it apart is the formulation. Daxxify's label describes a 35 amino acid peptide excipient, RTP004, that keeps the toxin from sticking to surfaces and helps it stay stable. Its ingredient list is L-histidine, polysorbate 20, the RTP004 peptide and trehalose, with no human albumin. Botox Cosmetic and Xeomin both list human albumin.
Daxxify's cosmetic approval is specific: moderate to severe glabellar lines, the vertical 11s between the brows, in adults. It is also approved for cervical dystonia, a neck muscle condition, at much higher doses. Treating the forehead, crow's feet or other areas with Daxxify is off-label, which is legal and common in medical practice, and your provider should tell you when an area is off-label.
Units and cost
Daxxify is counted in its own units. The FDA label gives a dose for one area only.
| Area | Daxxify units | Price at BHRC Henderson |
|---|---|---|
| Frown lines (11s), FDA-approved area | 40, as five injections of 8 units | By the vial, at consultation |
| Forehead lines, off-label | Set by your injector | By the vial, at consultation |
| Crow's feet, off-label | Set by your injector | By the vial, at consultation |
The label dose for frown lines is 40 units, repeated no more often than every three months. We do not publish unit ranges for off-label areas because the label does not give them. Daxxify is supplied in 50-unit and 100-unit vials. Source: DAXXIFY prescribing information.
Where to get it
Only clinics whose own price list includes Daxxify are listed. Today that is Henderson.
| Clinic | How it is sold | Price |
|---|---|---|
| Henderson, The District at Green Valley Ranch | Full vial (Nevada rule) | Priced at consultation |
Our West Hollywood, West Los Angeles, Valencia, Westlake Village, Downtown Summerlin, Paradise Valley and Houston clinics offer Botox, Dysport and Xeomin. Henderson is an independently owned BHRC franchise. Daxxify earns points in REVA Revance Rewards; Revance sets the program terms.
Comparison
All four are botulinum toxin type A and relax the same muscles. What differs is the formulation, the units and what each label says about timing.
The FDA label does not give a duration in months for frown lines. What it does say is that in the two main trials every subject was followed for at least 24 weeks, with results charted out to 36 weeks, and that treatment should not be repeated more often than every three months. Botox Cosmetic's label puts its frown-line effect at about three to four months, Dysport's says up to four months and Xeomin's says up to 12 to 16 weeks. Your own result depends on dose, muscle strength and the area treated.
The label does not state an onset time. Revance reports that in clinical trial diaries people saw a measurable improvement within two days, and as early as the next day. For comparison, Botox Cosmetic's label describes effects starting one to two days after injection, and Xeomin's gives a median onset of two to seven days.
The Daxxify label says its units cannot be compared to or converted into units of any other botulinum toxin. The frown-line label dose is 40 units of Daxxify, against 20 units of Botox Cosmetic, 20 of Xeomin and 50 of Dysport. A bigger number does not mean a stronger treatment, and a per-unit price cannot be compared across brands. Compare the cost of the treated area.
Daxxify uses the RTP004 peptide and has no human albumin in its ingredient list. Botox Cosmetic and Xeomin list human albumin; Dysport lists human albumin and lactose. Whether that matters for you is a conversation with your provider, not a reason to rank one brand above another.
Neither is better for everyone. If you are planning around longer gaps between treatments, ask your provider what the trials showed and how your muscles have responded to other toxins. At BHRC, Daxxify is offered at Henderson; Botox, Dysport and Xeomin are offered at every corporate clinic.
Safety
In the frown-line trials the most common reactions were headache (6% vs 2% on placebo), eyelid drooping (2% vs 0%) and facial paresis, including facial asymmetry (1% vs 0%). Injection site reactions occurred in 6% of people on Daxxify and 6% on placebo.
Like every botulinum toxin, Daxxify carries an FDA boxed warning that its effect can spread from the injection area and cause symptoms such as swallowing, speaking or breathing difficulty, hours to weeks after treatment. Seek medical care straight away if that happens.
Daxxify is contraindicated if you are allergic to any botulinum toxin product or to any ingredient in Daxxify, or if there is an infection at the injection site. Tell your provider about neuromuscular conditions, eye or eyelid problems, heart or bleeding problems, past facial surgery, and any other toxin you have had recently.
There are no human data on Daxxify in pregnancy or breastfeeding. Cosmetic treatment is usually postponed until you are done; discuss it with your provider.
In the glabellar-line studies, 2,786 people received up to three treatments over 120 weeks. Antibodies formed in 0.8% (to the toxin) and 1.2% (to the peptide), and no one developed neutralizing antibodies.
Treatment areas
Frown lines
40 units, label dose
The FDA-approved use: the vertical 11s between the brows.
Forehead lines
Off-label
Dose set by your injector.
Crow's feet
Off-label
Dose set by your injector.
How it works
The same three steps as any botulinum toxin.
Your injector places Daxxify into the muscles that crease the skin between the brows: two points in each corrugator muscle and one in the procerus, 8 units each.
Daxxify blocks the release of acetylcholine at the nerve ending, so the muscle receives a weaker signal to contract.
The muscle relaxes and the frown line softens. Movement returns gradually as the nerve endings recover.
Which product
Timing as each product's FDA label or manufacturer states it. Units are not interchangeable.
Starts working: within 2 days in trial diaries (Revance). Lasts: trials followed at least 24 weeks; no month figure on the label. daxibotulinumtoxinA by Revance, peptide formulation, 40-unit frown-line dose. Offered at BHRC Henderson.
Starts working: 1 to 2 days (label). Lasts: about 3 to 4 months (label). onabotulinumtoxinA by Allergan Aesthetics, 20-unit frown-line dose. Offered at every BHRC clinic.
Starts working: median 2 to 3 days in trials. Lasts: up to 4 months (label). abobotulinumtoxinA by Galderma, 50-unit frown-line dose. Offered at every BHRC clinic.
Starts working: median 2 to 7 days (label). Lasts: up to 12 to 16 weeks (label). incobotulinumtoxinA by Merz, 20-unit frown-line trial dose. Offered at every BHRC clinic.
Good to know
The approved area first, then the off-label uses that come up in consultation.
The only cosmetic area on Daxxify's US label: 40 units in five injections. In the trials 74% of people reached the success measure at week four.
Off-label. The forehead muscle lifts the brows, so it is dosed with care and usually treated with the frown lines.
Off-label. Lines at the outer eyes that show when you smile.
Your injector sets a Daxxify dose for you. The label says units cannot be converted from another toxin, and it should not be given within three months of a previous Daxxify treatment.
Aftercare
A short appointment, and you can go back to your day.
Your provider reviews your health history, any toxin you have had before and how your face moves, then injects with a fine needle.
Avoid rubbing or massaging the area and skip hard exercise until the next day. Your provider gives you exact aftercare.
Small bruises at injection points can happen with any injectable.
Get medical help straight away for any trouble swallowing, speaking or breathing, or new muscle weakness, as the label advises.
Aftercare
Your result lasts longer when what you use at home is doing the same work. This is the routine our providers start most patients on, dispensed through the practice. Not sure it is right for your skin? Take the skin quiz, or ask your provider to build one around the treatment you are having.
skinbetter science
An exfoliating foam cleanser for normal to oily skin, for a brighter and more refined look without a separate scrub.
skinbetter science
A morning antioxidant serum with a broader antioxidant blend than a single-ingredient vitamin C.
skinbetter science
skinbetter science's most recognized product, and the one most people start with. AlphaRet pairs a retinoid with an alpha hydroxy acid in a single overnight step.
skinbetter science
An eye gel with a visible short-term tightening effect alongside longer-term peptide work.
All four steps together. Dispensed by the practice and shipped to you, or picked up at any of our 22 centers.
Is it for you
Daxxify treats frown lines caused by movement. It does not replace lost volume.
These are things to discuss, not automatic disqualifications, except an allergy to a botulinum toxin or a Daxxify ingredient.
Your timeline
Timing as the label and Revance describe it.
Frequently asked
At BHRC, Daxxify is offered at our Henderson clinic in The District at Green Valley Ranch. Revance also lists providers on its own locator at daxxify.com.
Not at the moment. Our West Hollywood clinic near Beverly Hills, West Los Angeles, Valencia, Westlake Village and Downtown Summerlin in Las Vegas offer Botox, Dysport and Xeomin. Daxxify is on the price list at our Henderson clinic.
BHRC Henderson prices Daxxify at consultation. In Nevada neurotoxin is sold by the full vial, and Daxxify comes in 50-unit and 100-unit vials, so the price depends on the vial your provider recommends.
Daxxify's FDA label does not state a duration in months. In its two main trials every subject was followed for at least 24 weeks, with results charted to 36 weeks, and the label says not to retreat more often than every three months. Ask your provider what to expect for your muscles.
The label does not give an onset time. Revance reports that people in its trials saw a measurable improvement within two days, and some by the next day.
The FDA label dose is 40 units, given as five injections of 8 units. Doses for other areas are set by your injector and are off-label.
No. The label says Daxxify units cannot be compared to or converted into units of any other botulinum toxin. The frown-line label dose is 40 units of Daxxify and 20 units of Botox Cosmetic, so compare the cost of the area, not the unit.
Neither is better for everyone. Both are botulinum toxin type A and work the same way. Daxxify has a peptide formulation without human albumin; Botox Cosmetic has more FDA-approved cosmetic areas. Your provider can explain which suits your goals.
Temporary improvement of moderate to severe frown lines between the brows in adults (approved 2022), and cervical dystonia in adults (added in 2023).
Only off-label. Daxxify's US cosmetic approval covers frown lines between the brows. Your provider should tell you when a treatment is off-label.
In the frown-line trials the most common were headache (6%), eyelid drooping (2%) and facial paresis (1%). Like every botulinum toxin, Daxxify has a boxed warning about the effect spreading beyond the injection area.
Not before it is mixed. The label allows unopened vials to be stored at room temperature or in a refrigerator, in the carton. Once reconstituted it must be refrigerated and used within 72 hours.
Yes. Your injector sets a Daxxify dose for you rather than converting your Botox units, and takes your recent treatments into account.
Yes. Daxxify earns points in REVA Revance Rewards, Revance's free points-based loyalty program, which also covers the Teoxane RHA Collection and SkinPen. Revance's site lists 250 points, worth $25, for each Daxxify treatment and 250 welcome points when you join. Points are earned and redeemed at participating providers, and Revance sets the terms.
Enhance your results
Daxxify relaxes movement. These treat volume and skin quality.
Botox, Dysport and Xeomin side by side.
Learn MoreFor lines that are there at rest, and for lips and cheeks.
Learn MoreGalderma's toxin, priced per unit at our corporate clinics.
Learn MoreDaxxify, Botox, Dysport and Xeomin in Henderson.
Learn MoreNeurotoxin is a prescription medicine and is injected by licensed medical providers.
Every medical statement on this page comes from the FDA prescribing information or Revance, listed in our sources.
We only list a clinic for Daxxify when its own price list includes it.
Find a center
Daxxify is offered at BHRC Henderson. Tap the clinic for directions, hours and booking.
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Start your journey
Book a consultation at BHRC Henderson. Your provider will review your history with other toxins, explain on-label and off-label options, and confirm the vial and price before anything is injected.
Medically reviewed by the BHRC clinical team. Last reviewed November 2026.
This page is for general information and is not medical advice. Treatment suitability, pricing and results vary by individual and are confirmed at consultation with a licensed provider.
