BHRC BLOG

Restylane Fillers: Full Product Guide, What Each Treats & Results

Restylane is a family of hyaluronic acid (HA) fillers manufactured by Galderma — one of the two major HA filler brands used in medical aesthetics worldwide. The Restylane line covers a spectrum of formulations, each engineered for a specific tissue depth, treatment area, and correction goal. BHRC providers use Restylane products across the face and hands depending on what the patient’s anatomy and goals require.

The Restylane Product Family

Galderma offers two core manufacturing technologies in the Restylane line — NASHA (Non-Animal Stabilized Hyaluronic Acid) for precise, particle-based placement, and OBT (Optimal Balance Technology) for products that need flexible, natural-feeling integration with mobile tissue.

• Restylane-L — the original, versatile formulation. Used for moderate facial lines, nasolabial folds, and general facial contouring. The “-L” indicates it contains lidocaine for patient comfort.
• Restylane Lyft — denser, higher G’ (lift capacity) formulation for cheek augmentation, cheek contouring, and back-of-hand rejuvenation (FDA-cleared for hands).
• Restylane Kysse — OBT formulation specifically engineered for the lips. Designed to move naturally with lip expressions while maintaining fullness. FDA-cleared for lip augmentation.
• Restylane Contour — designed for cheek contouring and midface augmentation with XpresHAn Technology for natural movement across expressions.
• Restylane Eyelight — ultra-soft formulation for the under-eye (tear trough) area, where lumps and lumpiness from stiffer products would be visible.
• Restylane Defyne — for deeper nasolabial folds and marionette lines; engineered for areas with moderate-to-high facial movement.
• Restylane Refyne — for moderate lines with significant movement, where flexibility is important to prevent the filler from looking stiff at rest.

What Restylane Treats

• Nasolabial folds and marionette lines — Restylane-L, Defyne, or Refyne depending on severity and movement pattern
• Cheek volume loss — Restylane Lyft or Contour for midface augmentation
• Lip augmentation and definition — Restylane Kysse for natural-feeling lip volume and border definition
• Under-eye hollows (tear trough) — Restylane Eyelight placed under the orbicularis muscle to soften the shadow
• Back of hands — Restylane Lyft is FDA-cleared for hand rejuvenation, restoring volume that makes tendons and veins less visible
• Chin and jaw contouring — Restylane Lyft or Defyne for structural support

Restylane vs. Juvederm

Both are hyaluronic acid filler brands — both safe, effective, and widely used. The differences are in manufacturing technology, feel, and product-to-area matching:

• Particle structure: Restylane uses NASHA technology with discrete gel particles; Juvederm (VYCROSS) is a smoother, more homogenous gel. Restylane’s particle structure can offer more precise placement; Juvederm’s smooth gel integrates very naturally in highly mobile areas.
• Duration: Both families have products lasting 6–18 months depending on area. Juvederm Voluma tends to last longer in the cheeks (18+ months); Restylane Lyft is typically 12 months in the same area.
• Swelling pattern: Juvederm products tend to produce slightly more post-treatment swelling due to higher water-absorption capacity; Restylane products often show final results faster.

Provider preference and patient anatomy both factor into which product is chosen. BHRC providers are trained in both lines and select based on what will achieve the most natural result for each individual.

The Restylane Experience at BHRC

All Restylane formulations contain lidocaine for comfort. Topical numbing cream is applied 15–20 minutes before treatment for more sensitive areas. Most treatments take 20–40 minutes. Bruising and swelling are possible for 3–7 days; final results are typically visible at 2 weeks. Results are fully reversible with hyaluronidase if needed.

Frequently Asked Questions

How long does Restylane last?

Duration varies by product and area: lip fillers (Kysse) last approximately 12 months; nasolabial folds 9–12 months; cheeks (Lyft) approximately 12 months; hands (Lyft) approximately 12 months. Individual metabolism affects all estimates.

Is Restylane safe for under-eye filler?

Restylane Eyelight is specifically formulated for under-eye placement and is the product BHRC providers use in this area. Tear trough treatment requires a very experienced injector — the under-eye is vascular and requires precise depth and product choice to avoid complications like the Tyndall effect (bluish discoloration from superficially placed HA).

Can Restylane be dissolved?

Yes. All Restylane products are hyaluronic acid and can be dissolved with hyaluronidase. This makes correction possible if a patient is unhappy with the result or if the product migrates from the intended placement area.